The Vazquez Lab


Studying the evolution of longevity-associated traits and the gene regulatory networks that govern them in extraordinarily long-lived mammals at all levels of life.

Join us! Meet the team

We’re recruiting undergrads, grad students, and postdocs interested in studying the evolution of aging using pangenomics, molecular and cellular biology, and functional evolutionary genomics.

Latest News

2024-10-10 2 min read
New preprint: "Extensive longevity and DNA virus-driven adaptation in nearctic Myotis bats"
New preprint: "Extensive longevity and DNA virus-driven adaptation in nearctic Myotis bats"

Our newest paper, featuring our work on understanding the evolution of longevity-associated traits and innate immunity in Myotis bats. The publication features our cell line resources and near-complete reference genomes for 9 species Myotis bats.

PDF Preprint
2024-05-05 2 min read
First-ever Marine Mammal Symposium on Physiology, Toxicology, and Cell Biology
First-ever Marine Mammal Symposium on Physiology, Toxicology, and Cell Biology

We had a great time meeting new and old friends and colleagues to discuss current work in physiology, toxicology, and cell biology on marine species! As a result of our discussions on the current challenges and opportunities in marine mammal research, we penned a position paper, which has since been published in Frontiers in Marine Science.

PDF Read our Position Paper

Latest Publications

Melissa Sui, Joanne Teh, Kayleigh Fort, Daniel Shaw, Peter Sudmant, Tsuyoshi Koide, Jeffrey M Good, Juan M Vazquez, Rachel B Brem (2025). Avid lysosomal acidification in fibroblasts of the Mediterranean mouse Mus spretus. bioRxiv.org: the preprint server for biology.

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Juan Manuel Vazquez, Jane I Khudyakov, Carla B Madelaire, Céline a Godard-Codding, Heli Routti, Emily K Lam, Elizabeth R Piotrowski, Greg B Merrill, Jillian H Wisse, Kaitlin N Allen, Justin Conner, Pierre Blévin, Demetri D Spyropoulos, Anders Goksøyr, José Pablo Vázquez-Medina (2024). Ex vivo and in vitro methods as a platform for studying anthropogenic effects on marine mammals: four challenges and how to meet them. Frontiers in Marine Science.

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Juan M Vazquez, M Elise Lauterbur, Saba Mottaghinia, Melanie Bucci, Devaughn Fraser, Genavieve Gray-Sandoval, Léa Gaucherand, Zeinab R Haidar, Melissa Han, William Kohler, Tanya M Lama, Amandine Le Corf, Sarah Maesen, Dakota McMillan, Stacy Li, Johnathan Lo, Carine Rey, Samantha Lr Capel, Michael Singer, Kathleen Slocum, William Thomas, Janet Debelak Tyburec, Sarah Villa, Richard Miller, Michael Buchalski, Jose Pablo Vazquez-Medina, Sébastien Pfeffer, Lucie Etienne, David Enard, Peter H Sudmant (2024). Extensive longevity and DNA virus-driven adaptation in nearctic Myotis bats. bioRxiv.org: the preprint server for biology.

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Nadya Ali, Olga Amelkina, Rachel M Santymire, Klaus-Peter Koepfli, Pierre Comizzoli, Juan M Vazquez (2024). Semen proteome and transcriptome of the endangered black-footed ferret (Mustela nigripes) show association with the environment and fertility outcome. Scientific reports.

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Stacy Li, Juan Manuel Vazquez, Peter H Sudmant (2023). The evolution of aging and lifespan. Trends in genetics: TIG.

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